PCOS: I'm Actually Losing Weight... ![]() Drug combination promotes weight loss in polycystic ovary syndrome. SAN FRANCISCO- - Women with polycystic ovary syndrome, or PCOS, lost significantly more weight when they took two drugs that are traditionally used to treat diabetes, rather than either drug alone, a study from Slovenia demonstrates. The results will be presented Monday at The Endocrine Society's 9. Annual Meeting in San Francisco. PCOS is the leading cause of infertility among women. In the United States, the disorder affects approximately 5 million women, according to the U. S. Department of Health and Human Services Office of Women's Health. ![]() This translates to 1 in 1. The disease probably is genetic, although the exact causes are still unknown. In PCOS, the ovaries produce excessive amounts of male sex hormones, or androgens. The name of the disease derives from small cysts that form on the ovaries, which do not produce enough of the hormone that triggers ovulation. When this occurs, the ovarian follicles, which have filled with fluid in preparation for ovulation, remain as cysts when ovulation fails to take place. In addition to infertility, symptoms include excessive hair growth in areas that usually are relatively hairless; obesity; menstrual irregularity; thinning or balding hair on the scalp; prediabetes or diabetes; and anxiety or depression. Weight loss in these women leads to higher chances of conception, improved pregnancy outcomes and improved metabolic profile. Treatment varies depending upon the severity of the disease, and includes lifestyle modifications and drug therapy. Some of the same medications that are used to treat diabetes also improve PCOS symptoms. One of these medications, metformin, works by regulating the hormone insulin and by suppressing androgen activity, which, in turn, helps control blood- sugar levels and has beneficial effects on ovarian function. The problem with metformin, however, is that it does not always aid with weight loss. Because of this, investigators examined different drug combinations to see which ones caused the most weight loss. In addition to metformin, they administered another diabetes medication called liraglutide, both alone and in combination with metformin, to determine which approach led to the greatest amount of weight loss. They found that patients who took the combined drugs lost 6. Furthermore, 2. 2 percent of participants on the combined treatment lost a significant amount of weight, defined as 5 percent or more of their body weight, compared to 1. No one in the metformin group achieved this amount of weight loss. In terms of body- mass index and waist circumference, the combined- treatment group saw greater improvements than either of the single- medication groups. The nausea did improve with time, however, and was not associated with weight loss. Study participants comprised 3. PCOS who had lost less than 5 percent of their body weight on a six- month course of metformin preceding the study. Their average age was 3. Investigators randomly assigned them to one of three treatment groups for the 1. The University Medical Center Ljubljana, Slovenia, funded the study.###Founded in 1. ![]() ![]() The Endocrine Society is the world's oldest, largest and most active organization devoted to research on hormones and the clinical practice of endocrinology. Society members represent all basic, applied and clinical interests in endocrinology. The Endocrine Society is based in Chevy Chase, Maryland. To learn more about the Society and the field of endocrinology, visit our site at http: //www. ![]() Black Women Losing Weight. Don't put your dreams. Black Weight Loss Success.![]() ![]() ![]() 7 Fitness Tips for Women with PCOS. Let me offer you fitness tips for women with PCOS. How to Stick to Your Weight Loss Combatting Polycystic Ovary Disease Through Diet. Video Education Center. Explore SoulCysters.com's board 'PCOS Weight Loss Stories' on Pinterest. ![]() How to Lose Weight With PCOS. Polycystic ovary syndrome (PCOS). Some dietitians are experienced with PCOS and weight loss. Polycystic Ovarian Syndrome Treatment & Management. However, in some obese patients with PCOS, weight loss has improved menstrual regularity. Forum: Hair Loss/Hair Growth. Has anyone had success growing some of their hair back. Weight Loss Surgery & PCOS. Try a PCOS Weight Loss Plan; What's Your Ideal Fertility Weight? 5 PCOS Diet Strategies If you have polycystic ovary syndrome (PCOS). Weight Loss; Success Stories; PCOS Quiz; SHOP; My Account; About Insulite Health; Meet Our Team; Contact us. Women with PCOS (Polycystic Ovarian Syndrome). I have PCOS and have been on Metformin for 2 weeks, does anyone have a success story? Top 10 signs of pregnancy. ![]()
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